Prevalence of asthma
100-150 million people around the globe are suffering from asthma according to World Health Organization (WHO). 15-20 million asthmatics are there in India.
Worldwide 180,000 people die of asthma annually.
Asthma is the chronic inflammatory disease of the airways that causes periodic attacks of coughing, wheezing, shortness of breath, and chest tightness. Asthma can occur at all age groups but usually starts in childhood.
The pathophysiology of asthma is complex and involves airway inflammation, intermittent airflow obstruction, and bronchial hyperresponsiveness. Asthma is associated with mast cells, eosinophils, and T lymphocytes. Mast cells release chemicals like histamine which in turn causes nasal stuffiness and dripping in cold or hay fever, constriction of airway in asthma, and itching in skin allergy. These cells along with other inflammatory cells cause airway inflammation leading to airway hyperresponsiveness and obstruction leading to symptoms of asthma.
To read the full article please click here